Turmeric longa has always been traditionally used in Asian countries as an herb because of its antioxidant, anti-inflammatory, antimutagenic, antimicrobial, and anticancer properties .
The therapeutic properties of turmeric, have been known for thousands of years; however, the ability to determine the exact mechanism of action and bioactive components have only recently been studied. All of the healing properties and benefits that come with taking turmeric, are solely due to curcumin, which actually constitutes only 2% of turmeric itself! In fact, medical and scientific studies and research have shown that to achieve the same effects as a concentrated dose of curcumin, one would need to take about 50 times the recommended dose of turmeric! In fact, there are supplements and concentrated preparations exclusively based on curcumin on the market to solve this problem. Ingesting curcumin alone does not result in health benefits because of its poor bioavailability, which seems to be mainly due to poor absorption and rapid elimination by our bodies. There are several components that can increase its bioavailability, for example, piperine, the main active component of black pepper, blocking the curcumin maetabolic pathway has been shown to increase its bioavailability by 2000%. Curcumin combined with enhancing agents offers multiple health benefits:
- POWERFUL ANTIFIAMMATORY: Inflammation has been identified in the development of many diseases and chronic pain conditions. The various studies have repeatedly confirmed that curcumin boasts powerful anti-inflammatory properties due to its amazing ability to inhibit enzymes such as lipoxygenase or cyclooxygenase; these are two of the main molecules that trigger inflammatory reactions. Thus, the use of curcumin is highly recommended for those suffering from various inflammatory conditions such as arthritis, osteoarthritis, osteoarthritis, carpal tunnel syndrome, conjunctivitis, pancreatitis, colitis, cystitis, Crohn's disease, respiratory tract inflammation(sore throat, cough, bronchitis, and pneumonia), colds, and neurodegenerative diseases.
- ANTIOXIDANT: Curcumin acts through theactivation of special enzymes that are able to neutralize free radicals, the famous molecules responsible for cellular aging. They are also capable of damaging cell membranes through peroxidation and causing oxidative damage to DNA. These processes can cause the emergence of many neurodegenerative diseases. Curcumin is a valuable ally in preventing and counteracting the onset of many diseases.
- ACTIVATES METABOLISM: The anti-inflammatory action of curcumin has many benefits on the body, in fact it can be implicated for example in individuals with: insulin resistance, hyperglycemia, hypertension, elevated triglyceride levels, and obesity, particularly visceral obesity. Curcumin has been shown to attenuate several of these issues, improving insulin sensitivity, suppressing adipogenesis, and reducing elevated blood pressure, inflammation, and oxidative stress. In addition, there is evidence that curcuminoids modulate the activity of genes and enzymes involved in lipoprotein metabolism leading to a reduction in plasma triglycerides and cholesterol. Therefore addressing inflammation is important.
Curcumin has received worldwide attention for its many health benefits, which appear to act primarily through its antioxidant and anti-inflammatory mechanisms. These benefits are best achieved when curcumin is combined with agents such as piperine, which significantly increase its bioavailability. Research suggests that it may also aid in the management of exercise-induced inflammation and muscle pain, thereby improving recovery and performance in active people, to help inflammatory and degenerative eye conditions, and for anxiety states.